Ask yourself this: Would you want your surgeon to perform surgery on you without washing up first?!!
All I can think about is how often we are in contact with germs, viruses, fungi, and bacteria that is harmful and or deadly to us. I prefer to lose a little of the good bacteria to wash off the deadly and harmful stuff. Plus I certainly do not want any health care worker touching me who has not washed up after seeing their last patient. Like someone else mentioned, there is a reason why soap was invented and why we continue to use it for so many centuries.