Someone might have mentioned this already, but in case they didn't: I also lightly squeeze a bit of air out of the bottle before I close the cap, put my finger on it, and shake it. That way, when the cap is released after shaking, the bottle will suck in a bit of air to equalize, rather than spraying out some of the contents. Can't remember where I learned that one, but it really works!another tip from my lab tech days -- always keep a finger over the cap or closure when you shake a bottle to mix the contents. If you shake that TD bottle as hard as I do, a cap might easily go flyin' without a protective finger in place.